Motif ID: FOX{I1,J2}.p2

Z-value: 1.267


Transcription factors associated with FOX{I1,J2}.p2:

Gene SymbolEntrez IDGene Name
FOXI1 2299 forkhead box I1
FOXJ2 55810 forkhead box J2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOXI1chr5_+_1694654780.185.0e-01Click!
FOXJ2chr12_+_80765080.078.1e-01Click!


Activity profile for motif FOX{I1,J2}.p2.

activity profile for motif FOX{I1,J2}.p2


Sorted Z-values histogram for motif FOX{I1,J2}.p2

Sorted Z-values for motif FOX{I1,J2}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOX{I1,J2}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_149960218 2.325 GIMAP6
GTPase, IMAP family member 6
chr5_+_159368690 1.526 TTC1
tetratricopeptide repeat domain 1
chr15_-_53587723 1.299 NM_001033559
NM_001033560
NM_130810
DYX1C1


dyslexia susceptibility 1 candidate 1


chr3_-_184756101 1.288 NM_130446
KLHL6
kelch-like 6 (Drosophila)
chr13_+_22653059 1.237 NM_000231
SGCG
sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
chr12_+_47584159 1.211 NM_033124
CCDC65
coiled-coil domain containing 65
chr5_+_159368721 1.166 TTC1
tetratricopeptide repeat domain 1
chr22_-_41366550 1.126 NM_001165877
ATP5L2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G2
chr5_+_159368733 1.072 NM_003314
TTC1
tetratricopeptide repeat domain 1
chr12_-_12740387 1.055 NM_006143
GPR19
G protein-coupled receptor 19
chr10_+_15125900 0.967 NM_001039702
NM_018324
OLAH

oleoyl-ACP hydrolase

chr6_+_153060722 0.955 NM_025107
MYCT1
myc target 1
chr19_-_53305825 0.950 NM_001159322
NM_001159323
NM_003706
PLA2G4C


phospholipase A2, group IVC (cytosolic, calcium-independent)


chr22_+_36008465 0.949 CYTH4
cytohesin 4
chr22_-_23500682 0.930 NM_001008496
PIWIL3
piwi-like 3 (Drosophila)
chr16_+_80370400 0.919 PLCG2
phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr1_-_24112345 0.893 NM_001841
CNR2
cannabinoid receptor 2 (macrophage)
chr5_-_54317102 0.873 NM_001135604
NM_007036
ESM1

endothelial cell-specific molecule 1

chr22_+_36008511 0.831 CYTH4
cytohesin 4
chr4_+_86968069 0.808 ARHGAP24
Rho GTPase activating protein 24
chr3_-_121445831 0.751 NM_001168271
NM_153002
GPR156

G protein-coupled receptor 156

chr17_-_7471832 0.696 NM_133491
SAT2
spermidine/spermine N1-acetyltransferase family member 2
chr17_-_31219943 0.683 NM_152781
C17orf66
chromosome 17 open reading frame 66
chr19_-_60566419 0.675 NM_001145402
FAM71E2
family with sequence similarity 71, member E2
chr12_+_111375382 0.659 PTPN11
protein tyrosine phosphatase, non-receptor type 11
chr19_-_44722599 0.654 NM_153232
EID2
EP300 interacting inhibitor of differentiation 2
chr8_+_104452877 0.652 CTHRC1
collagen triple helix repeat containing 1
chr12_-_21649019 0.651 NM_021957
GYS2
glycogen synthase 2 (liver)
chr10_-_31328426 0.640 NM_001143769
ZNF438
zinc finger protein 438
chr15_+_22778233 0.620 SNRPN
small nuclear ribonucleoprotein polypeptide N
chr7_-_27186400 0.614 NM_153715
HOXA10
homeobox A10
chr2_-_95514205 0.602 NM_001164464
TRIM43
TRIM43B
tripartite motif containing 43
tripartite motif containing 43B
chr1_+_157246305 0.586 NM_005531
IFI16
interferon, gamma-inducible protein 16
chr11_+_112337299 0.574 NCAM1
neural cell adhesion molecule 1
chr13_-_35327798 0.571 NM_001195415
NM_001195416
NM_001195430
DCLK1


doublecortin-like kinase 1


chr5_-_59100194 0.568 NM_001197218
PDE4D
phosphodiesterase 4D, cAMP-specific
chr1_+_84536636 0.566 NM_001010971
SAMD13
sterile alpha motif domain containing 13
chr9_+_78305368 0.558 NM_001097636
GCNT1
glucosaminyl (N-acetyl) transferase 1, core 2
chr19_-_62348381 0.552 NM_052882
ZIM3
zinc finger, imprinted 3
chr19_+_57564981 0.540 NM_001145434
ZNF880
zinc finger protein 880
chr6_+_29963328 0.538 HLA-H
major histocompatibility complex, class I, H (pseudogene)
chr20_+_19818209 0.536 NM_018993
RIN2
Ras and Rab interactor 2
chr11_+_63060848 0.533 NM_004585
RARRES3
retinoic acid receptor responder (tazarotene induced) 3
chr5_-_94250357 0.532 MCTP1
multiple C2 domains, transmembrane 1
chr12_+_123339662 0.523 NM_181709
FAM101A
family with sequence similarity 101, member A
chr3_-_99236520 0.515 NM_001105580
GABRR3
gamma-aminobutyric acid (GABA) receptor, rho 3
chr7_+_150013716 0.513 NM_015660
GIMAP2
GTPase, IMAP family member 2
chr4_-_186815116 0.511 NM_001145674
NM_001145675
SORBS2

sorbin and SH3 domain containing 2

chr11_+_113436438 0.510 NM_001018011
ZBTB16
zinc finger and BTB domain containing 16
chr6_-_152681171 0.507 NM_015293
SYNE1
spectrin repeat containing, nuclear envelope 1
chr3_+_115495522 0.499 NM_173799
TIGIT
T cell immunoreceptor with Ig and ITIM domains
chr1_-_171286634 0.499 NM_005092
TNFSF18
tumor necrosis factor (ligand) superfamily, member 18
chr15_+_76345577 0.496 NM_001130183
DNAJA4
DnaJ (Hsp40) homolog, subfamily A, member 4
chr4_+_147316284 0.488 NM_007080
LSM6
LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr1_+_84382529 0.488 NM_182948
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr5_+_140546839 0.485 NM_019119
PCDHB9
protocadherin beta 9
chr3_-_69381995 0.479 FRMD4B
FERM domain containing 4B
chr4_+_68107039 0.479 NM_012108
STAP1
signal transducing adaptor family member 1
chr13_+_48968097 0.473 PHF11
PHD finger protein 11
chr9_+_139047441 0.472 C9orf139
chromosome 9 open reading frame 139
chrX_+_15428820 0.469 NM_203281
BMX
BMX non-receptor tyrosine kinase
chr6_-_137536412 0.467 NM_052962
NM_181309
NM_181310
IL22RA2


interleukin 22 receptor, alpha 2


chr2_-_188021117 0.466 NM_005795
CALCRL
calcitonin receptor-like
chr10_-_98021144 0.461 NM_001114094
NM_013314
BLNK

B-cell linker

chr19_-_14853166 0.457 NM_030901
OR7A17
olfactory receptor, family 7, subfamily A, member 17
chr6_+_114285209 0.453 NM_002356
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr1_+_66570363 0.453 NM_001037339
PDE4B
phosphodiesterase 4B, cAMP-specific
chr5_-_24680841 0.451 NM_006727
CDH10
cadherin 10, type 2 (T2-cadherin)
chr8_-_42742729 0.441 NM_004198
CHRNA6
cholinergic receptor, nicotinic, alpha 6
chr15_-_58706934 0.440 NM_002943
NM_134260
RORA

RAR-related orphan receptor A

chr9_+_119506274 0.438 NM_138554
TLR4
toll-like receptor 4
chr5_-_180009150 0.433 FLT4
fms-related tyrosine kinase 4
chr7_-_87687302 0.433 NM_003130
SRI
sorcin
chr13_-_32757835 0.433 NM_178006
STARD13
StAR-related lipid transfer (START) domain containing 13
chr14_+_57964148 0.431


chr4_-_70861301 0.428 NM_001891
CSN2
casein beta
chr13_+_31318828 0.424 EEF1DP3
eukaryotic translation elongation factor 1 delta pseudogene 3
chr11_-_59707074 0.424 NM_022349
NM_152851
NM_152852
MS4A6A


membrane-spanning 4-domains, subfamily A, member 6A


chr12_+_21175394 0.422 NM_006446
SLCO1B1
solute carrier organic anion transporter family, member 1B1
chr8_-_52884456 0.420 NM_144651
PXDNL
peroxidasin homolog (Drosophila)-like
chr1_-_67366807 0.417 NM_001013674
C1orf141
chromosome 1 open reading frame 141
chr2_-_32344192 0.415 NM_021209
NLRC4
NLR family, CARD domain containing 4
chr19_+_46121963 0.414 CYP2B7P1
cytochrome P450, family 2, subfamily B, polypeptide 7 pseudogene 1
chr11_-_102250876 0.413 NM_002426
MMP12
matrix metallopeptidase 12 (macrophage elastase)
chr12_+_7348194 0.409 NM_001080454
ACSM4
acyl-CoA synthetase medium-chain family member 4
chr4_-_186814852 0.405 SORBS2
sorbin and SH3 domain containing 2
chr3_-_122862447 0.405 NM_005335
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr1_-_171441234 0.403 TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr8_+_85258056 0.401 NM_173848
RALYL
RALY RNA binding protein-like
chr12_+_29193399 0.399 FAR2
fatty acyl CoA reductase 2
chr19_+_46762872 0.395 CEACAM21
carcinoembryonic antigen-related cell adhesion molecule 21
chr7_+_28441758 0.395 NM_004904
CREB5
cAMP responsive element binding protein 5
chr1_+_66570683 0.394 PDE4B
phosphodiesterase 4B, cAMP-specific
chr10_-_48426868 0.393 NM_001042357
NM_001042389
PTPN20B
PTPN20A
protein tyrosine phosphatase, non-receptor type 20B
protein tyrosine phosphatase, non-receptor type 20A
chr12_-_7487989 0.390 NM_174941
CD163L1
CD163 molecule-like 1
chr19_+_56958452 0.388 NM_001462
FPR2
formyl peptide receptor 2
chr14_-_46882144 0.388 NM_182830
MDGA2
MAM domain containing glycosylphosphatidylinositol anchor 2
chr9_+_106496480 0.388 NM_001004484
OR13D1
olfactory receptor, family 13, subfamily D, member 1
chr19_+_57540493 0.387 NM_173530
ZNF610
zinc finger protein 610
chr1_+_148389039 0.386 PLEKHO1
pleckstrin homology domain containing, family O member 1
chr1_-_161439487 0.385 NM_003617
RGS5
regulator of G-protein signaling 5
chr9_+_119506446 0.384 TLR4
toll-like receptor 4
chr13_-_73605914 0.378 NM_007249
KLF12
Kruppel-like factor 12
chr10_-_93992982 0.373 NM_001178137
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr12_+_27066768 0.373 MED21
mediator complex subunit 21
chr3_+_46423682 0.372 NM_003965
NM_001130910
CCRL2

chemokine (C-C motif) receptor-like 2

chr10_+_118295417 0.371 NM_000936
PNLIP
pancreatic lipase
chr5_+_357290 0.371 NM_020731
AHRR
aryl-hydrocarbon receptor repressor
chr3_-_122862391 0.371 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr7_+_119700924 0.371 NM_012281
KCND2
potassium voltage-gated channel, Shal-related subfamily, member 2
chr1_-_181540631 0.370 NM_170706
NMNAT2
nicotinamide nucleotide adenylyltransferase 2
chr4_+_91035025 0.368 NM_007351
MMRN1
multimerin 1
chr12_-_14929991 0.364 NM_000900
NM_001190839
MGP

matrix Gla protein

chr2_+_33514896 0.362 NM_170672
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr3_-_168853982 0.358 NM_178824
WDR49
WD repeat domain 49
chr7_-_87687276 0.357 SRI
sorcin
chr14_-_59701763 0.355 DHRS7
dehydrogenase/reductase (SDR family) member 7
chr19_+_9157269 0.354 NM_175883
OR7D2
olfactory receptor, family 7, subfamily D, member 2
chr2_-_175170674 0.352 WIPF1
WAS/WASL interacting protein family, member 1
chr11_+_128069203 0.352 FLI1
Friend leukemia virus integration 1
chr18_+_75261231 0.352 NM_172387
NM_172389
NFATC1

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1

chr7_-_149960612 0.351 NM_024711
GIMAP6
GTPase, IMAP family member 6
chr10_+_82163568 0.350 C10orf58
chromosome 10 open reading frame 58
chr5_-_88215034 0.349 NM_001193350
NM_002397
MEF2C

myocyte enhancer factor 2C

chr11_+_114054409 0.346 NM_182495
FAM55B
family with sequence similarity 55, member B
chr1_+_190811479 0.345 NM_002922
RGS1
regulator of G-protein signaling 1
chr4_+_167013859 0.343 NM_012464
TLL1
tolloid-like 1
chr12_+_54132264 0.343 NM_054105
OR6C2
olfactory receptor, family 6, subfamily C, member 2
chr15_+_37330176 0.342 NM_207445
C15orf54
chromosome 15 open reading frame 54
chr12_+_27066749 0.340 NM_004264
MED21
mediator complex subunit 21
chr19_-_11550765 0.339 NM_001111035
NM_001111036
ACP5

acid phosphatase 5, tartrate resistant

chr19_-_56946911 0.335 NM_001193306
NM_002029
FPR1

formyl peptide receptor 1

chr2_+_61225710 0.334 NM_001143960
C2orf74
chromosome 2 open reading frame 74
chr1_+_218768170 0.332 NM_018650
MARK1
MAP/microtubule affinity-regulating kinase 1
chr2_+_237143118 0.331 NM_020311
CXCR7
chemokine (C-X-C motif) receptor 7
chr16_+_29971955 0.331 ALDOA
aldolase A, fructose-bisphosphate
chr19_+_48772791 0.330 NM_001193621
LOC390940
hypothetical protein LOC390940
chr9_+_119506428 0.330 TLR4
toll-like receptor 4
chrX_+_38096679 0.328 NM_000531
OTC
ornithine carbamoyltransferase
chrX_+_77889861 0.326 NM_005296
LPAR4
lysophosphatidic acid receptor 4
chr9_-_94284455 0.325 ASPN
asporin
chr21_-_31041390 0.324 NM_181617
KRTAP21-2
keratin associated protein 21-2
chr1_+_156229686 0.324 NM_018240
KIRREL
kin of IRRE like (Drosophila)
chr4_-_130233855 0.318 NM_144643
SCLT1
sodium channel and clathrin linker 1
chr7_-_75256999 0.318 NM_006072
CCL26
chemokine (C-C motif) ligand 26
chr5_-_121842680 0.317


chr11_+_101693403 0.316 NM_001165
NM_182962
BIRC3

baculoviral IAP repeat containing 3

chr11_-_30910074 0.315 NM_020869
DCDC5
doublecortin domain containing 5
chr11_-_113935789 0.314 NM_152315
FAM55A
family with sequence similarity 55, member A
chrX_-_74660024 0.313 NM_001146256
NM_001146257
NM_144969
ZDHHC15


zinc finger, DHHC-type containing 15


chr5_-_180009222 0.312 NM_002020
NM_182925
FLT4

fms-related tyrosine kinase 4

chr9_+_115212755 0.312 NM_152786
C9orf43
chromosome 9 open reading frame 43
chr19_+_55627971 0.311 NM_004533
MYBPC2
myosin binding protein C, fast type
chr10_-_131652007 0.311 NM_001005463
EBF3
early B-cell factor 3
chr2_-_2313894 0.311 NM_015025
MYT1L
myelin transcription factor 1-like
chr11_-_63841556 0.311 NM_016404
TRMT112
tRNA methyltransferase 11-2 homolog (S. cerevisiae)
chr6_-_41781655 0.307 TFEB
transcription factor EB
chr15_-_38387410 0.307 NM_004573
PLCB2
phospholipase C, beta 2
chr12_-_16649211 0.307 LMO3
LIM domain only 3 (rhombotin-like 2)
chr14_-_91268136 0.306 NM_024764
CATSPERB
cation channel, sperm-associated, beta
chr2_-_225519974 0.305 DOCK10
dedicator of cytokinesis 10
chr12_+_8216416 0.305 NM_001004328
ZNF705A
zinc finger protein 705A
chr11_-_123182266 0.304 NM_001005325
OR6M1
olfactory receptor, family 6, subfamily M, member 1
chr3_+_110611526 0.303 NM_001145553
FLJ25363
hypothetical LOC401082
chr1_+_158975662 0.302 NM_021181
SLAMF7
SLAM family member 7
chr15_-_38387357 0.300 PLCB2
phospholipase C, beta 2
chr13_-_109600709 0.299 COL4A1
collagen, type IV, alpha 1
chr6_-_123999640 0.299 NM_006073
TRDN
triadin
chr12_-_9913199 0.299 CLEC2B
C-type lectin domain family 2, member B
chr2_-_219906142 0.299 NM_001007089
RESP18
regulated endocrine-specific protein 18 homolog (rat)
chr1_-_85515174 0.298 NM_003921
BCL10
B-cell CLL/lymphoma 10
chr1_+_32512298 0.297 NM_001042771
LCK
lymphocyte-specific protein tyrosine kinase
chr19_+_14554895 0.297 NM_207390
CLEC17A
C-type lectin domain family 17, member A
chr11_+_112337199 0.296 NM_000615
NM_001076682
NM_181351
NCAM1


neural cell adhesion molecule 1


chr2_+_108271526 0.294 NM_001056
NM_176825
SULT1C2

sulfotransferase family, cytosolic, 1C, member 2

chr21_-_36774257 0.293 NM_001146079
NM_144492
CLDN14

claudin 14

chr17_+_54763689 0.293 NM_001005404
YPEL2
yippee-like 2 (Drosophila)
chr14_-_80475636 0.293 NM_152446
C14orf145
chromosome 14 open reading frame 145
chr2_+_39000007 0.292 NM_001145451
ARHGEF33
Rho guanine nucleotide exchange factor (GEF) 33
chrX_-_80344096 0.291 NM_030763
HMGN5
high-mobility group nucleosome binding domain 5
chr12_-_9913724 0.290 NM_005127
CLEC2B
C-type lectin domain family 2, member B
chr14_-_59701811 0.289 NM_016029
DHRS7
dehydrogenase/reductase (SDR family) member 7
chr11_+_128069183 0.287 FLI1
Friend leukemia virus integration 1
chr5_+_161427225 0.287 NM_000816
NM_198903
NM_198904
GABRG2


gamma-aminobutyric acid (GABA) A receptor, gamma 2


chr3_+_120799411 0.282 NM_015900
PLA1A
phospholipase A1 member A
chr1_-_27825178 0.282 NM_001042747
FGR
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chr10_-_14090459 0.281 FRMD4A
FERM domain containing 4A
chr3_-_113334657 0.280 NM_001190259
NM_001190260
NM_152785
GCET2


germinal center expressed transcript 2


chrX_+_8392870 0.280 NM_001001888
VCX3B
VCX3A
variable charge, X-linked 3B
variable charge, X-linked 3A
chr8_+_104452961 0.277 NM_138455
CTHRC1
collagen triple helix repeat containing 1
chr6_-_112682401 0.276 LAMA4
laminin, alpha 4
chr1_+_99884018 0.276 NM_017734
PALMD
palmdelphin
chr10_+_91164418 0.274 IFIT5
interferon-induced protein with tetratricopeptide repeats 5
chr2_-_151854619 0.273 NM_004688
NMI
N-myc (and STAT) interactor
chr1_+_218768146 0.273 MARK1
MAP/microtubule affinity-regulating kinase 1
chr19_-_44518516 0.271 NM_004877
GMFG
glia maturation factor, gamma
chr7_+_113513828 0.271 FOXP2
forkhead box P2
chr1_-_77457664 0.271 NM_005482
PIGK
phosphatidylinositol glycan anchor biosynthesis, class K
chr9_+_86474393 0.269 NM_001018065
NM_001018066
NTRK2

neurotrophic tyrosine kinase, receptor, type 2

chr22_-_45037882 0.268 NM_006071
PKDREJ
polycystic kidney disease (polycystin) and REJ homolog (sperm receptor for egg jelly homolog, sea urchin)

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.23 1.33e-05 GO:0005886 plasma membrane
1.23 2.04e-05 GO:0071944 cell periphery

Gene overrepresentation in function category:

enrichment   p-value GO term description
3.41 1.70e-02 GO:0004715 non-membrane spanning protein tyrosine kinase activity
7.11 2.27e-02 GO:0042805 actinin binding
1.63 4.44e-02 GO:0004984 olfactory receptor activity